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Guercio G, Di Palma MI, Pepe C, et al

Circadian influences on brain lipid metabolism and neurodegenerative diseases

Ponicidin could suppress pancreatic cancer cell proliferation via inducing ferroptosis by inhibiting the gamma-glutamyl cycle and regulating the polyunsaturated fatty acid metabolism in SW1990 cells [269]

Among the botanical drugs and polyherbal formulations reviewed, only Curcuma longa (Sukonthanonta, 2015) , Camellia sinensis (Roshdy et al., 2013), and GZFLW ( Curcuma longa were limited without the presence of a negative control group, while a systematic review of randomized clinical trials conducted on GZFLW revealed that the trials have a high risk of bias, with no description of the allocation concealment of the participants

This is mostly due to the biomarker's sensitivity, ease of measurement, and cost-effectiveness

UVB irradiation therefore disrupts the skin barrier through the depletion of bound ceramides, but the exact mechanism is unknown
