oncogene-driven changes in the metabolism of glutathione and mitochondria Role of GSH in carcinogenesis
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10.1016/j.tcb.2004.07.014 Trends Cell Biol

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The released cytokines enter the CNS via the circulation, driving microglial polarization from a homeostatic state toward a proinflammatory M1 phenotype

PMID 2768245

Glutamate cysteine ligase catalysis
