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The role of extrahepatic metabolism in the pharmacokinetics of the targeted covalent inhibitors afatinib, ibrutinib, and neratinib

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Recent studies highlight that mitochondrial dysfunction is a unifying mechanism in both Long COVID and ME/CFS
Using an interdisciplinary research approach, the aim is to identify mechanistic factors, acting alone and in combination, which impact aging and cancer risk, with the ultimate goal of designing and developing targeted prevention strategies

[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Gong, T., Liu, L., Jiang, W

Moore A, Morris ID: The involvement of insulin-like growth factor-I in local control of steroidogenesis and DNA synthesis of leydig and non-leydig cells in the rat testicular interstitium
