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While safe and beneficial in common dietary or therapeutic contexts, excessive or direct high-concentration exposure can be detrimental (Wang et al., 2019)

2024;10:e37613

the degree of the Cx43 loss correlated with the severity of symptoms, including nonmotor symptoms such as depression and sleep irregularities 209

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Dahuang-Wumei decoction protects against hepatic encephalopathy in mice: behavioural, biochemical, and molecular evidence
