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To counteract this, innovative approaches such as oxygen-generating nanoparticles (e.g., CAT-ecSNA-Cu) have been developed to sensitize tumors by modulating metabolic conditions [256]

Justus Liebigs Annalen der Chemie

In addition, research has shown that the absence of Nrf2 leads to the downregulation of vesicle-associated membrane protein 8, causing ferritin autophagy and the accumulation of nuclear receptor coactivator 4/apoferritin autophagosomes, which regulate ferritin synthesis and degradation, increasing LIP and thereby increasing susceptibility to ferroptosis [126]

These data indicate that catalase supplementation may be a potential pharmacological strategy for preventing or treating respiratory infections in people [99]

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Nutrients 4(10):13991440
