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The classic presentation of symptomatic B 12 deficiency occurs in Addison-Biermers disease, and is characterised by megaloblastic anaemia.9 This type of anaemia was the first condition to be linked to B 12 deficiency, and probably because of that, many doctors have the misconception that B 12 deficiency is ruled out in patients without anaemia

Some patients use one, some use both together
Frati et al., 2017
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