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Cancer Imaging 24 , 143 (2024)

In addition, there may be potential that these fragments are binding to these same receptors to elicit a zonulin-like effect in tight junction dysregulation, versus an inhibition of zonulin activity, although mechanistic studies need to be conducted to fully explore this possibility

In vitro , HSYA enhanced barrier function of IECs, reduced mitochondrial fragmentation and reactive oxygen species (ROS) accumulation, promoted proliferation and inhibited apoptosis by upregulating the expression of Bcl-2 and SOD2

Moreover, various mechanisms of transport pathways across BBB, several novel strategies, and alternative routes by which drugs can be properly delivered into CNS are also discussed

[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Eleftheriadou A.M., Mehl S., Renko K., Kasim R.H., Schaefer J.A., Minich W.B., Schomburg L