how is glutathione depleted Depletion in Mitochondrial Diseases g-glutamyl cycle. Depletion of glutathione
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10.4161/auto.20917 Autophagy 134 WangW.WangM.RuanY.TanJ.WangH.YangT.et al (2019)

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The significant interaction terms were decomposed by a simple slope analysis

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Flow cytometry revealed that quercetin increased the level of reactive oxygen species (ROS) and led to the destruction of the mitochondrial membrane by reducing certain protein levels, and finally it caused apoptosis in AGS cells

It acts as a selective antagonist of the sigma-1 receptor, a protein involved in various cellular processes, including neurotransmission and cell survival
