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Cells were lysed in NP40 buffer and protein was quantified using Pierce BCA Protein Assay Kit (Sigma)

391 CYP3A4 silencing blocked the cell cycle at the G2/M checkpoint and induced apoptosis in the MCF7 line via inhibiting Stat3 (Tyr-705) phosphorylation, thereby inhibiting anchorage-dependent growth and survival

References 1.Borbly A.A

For individuals with low plasma levels, topical application of vitamin C can be beneficial, particularly when optimized for absorption, such as in acidic conditions or when encapsulated in lipospheric forms

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