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A single IT administration of STS (16 mg/mml) in hyaluronic acid (HA) or P407 was given prior to IP injection of cisplatin (12 mg/kg) in rats

The CGI scale was also used as a tool to measure the improvement with oral glutathione supplementation

Directly and indirectly through multiple reactions which include enzymatic reactions, glutathione is oxidized to form GSSG, which is then reduced to GSH, its "active form" by yet another enzymatic reaction (3)

10.1038/s41421-020-00186-6 161 Sepich-PooreC.ZhengZ.SchmittE.WenK.ZhangZ

1 2 3 4 5 "Interorgan amino acid transport and its regulation"

3 AvanA.CarettiV.FunelN.GalvaniE.MaftouhM.HoneywellR