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This produces what is known as heartburn (but which is actually oesophagus burn)

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Upon oral intake, acetyl-l-carnitine supplements are rapidly deacetylated, i.e., converted back to l-carnitine and acetyl-CoA within the intestinal wall before absorption

doi: 10.1073/pnas.0635176100

Retrieved April 16, 2023

The trial included 60 adult participants (mean age approximately 49) who had clinical follow-up with labs every 2 months for up to 2 years, with some withdrawing early due to spontaneous remission, indication for definitive therapy (e.g., thyroidectomy or radioiodine), or an intolerance to the treatment