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Similar observations were also noted in previous textural analysis of peripheral nerves, in which diminished GLCM contrast was observed with the progression of amyotrophic lateral sclerosis 65
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With the development of nanotechnology, there has been a breakthrough in the harmless passage of drugs through the BBB for the treatment of CNS diseases

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J Am Geriatr Soc 65(5):10611066 Wile DJ, Toth C (2010) Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy

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