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(PubMed) Gerstenberger JP, Bauer SR, Van Blarigan EL, et al

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doi: 10.1007/BF00451097

Women with MTHFR deficiency are believed to be at a higher risk of miscarriage when pregnant, and all individuals with this gene mutation are also believed to be at a higher risk of developing thyroid issues, Alzheimer's disease, and cardiovascular complications