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The proposed mechanism involves glutamate modulation: NAC restores the cystine-glutamate antiporter (system Xc-), normalizing extracellular glutamate levels in brain regions associated with compulsive behaviors

Sugrue MM, Shin DY, Lee SW and Aaronson SA (1997) Wildtype p53 triggers a rapid senescence program in human tumor cells lacking functional p53

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Muriel Darnaudery, Lille University of Science and Technology, France Updates Copyright 2018 Berry, Bellisario, Panetta, Raggi, Magnifico, Arese and Cirulli