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Description
Both components consist of defined amino acid sequences associated with receptor-mediated endocrine signaling pathways
163165 AA is the main substrate of both isoforms, but LA is a known competitive substrate and inhibitor of prostaglandin formation by COX-1 and COX-2

[DOI] [PubMed] [Google Scholar] 77.Ayala A., Munoz M.F., Arguelles S

Similarly, when combined with anticoagulants like warfarin, substances like ginseng, garlic, and ginkgo biloba may raise the risk of bleeding (68)

Nagata K, Nishiyama C

Costunolide inhibits pulmonary fibrosis via regulating NF-kB and TGF-beta1/Smad2/Nrf2-NOX4 signaling pathways
