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Thus, although some of the damage in this experimental model of colitis reflects a direct erosive effect of TNBS and ethanol, their combined administration to rats reflects the in vivo operation of the damaging mechanisms elicited by TNBS, namely GSH depletion and ROS generation, indicating that ethanol facilitates the access of TNBS to the cell interior ensuring TNBS-induced GSH depletion and ROS generation

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Association of NRF2 with HIF-2-induced cancer stem cell phenotypes in chronic hypoxic condition

Osei-Hyiaman D, DePetrillo M, Pacher P, Liu J, Radaeva S, Btkai S, Harvey-White J, Mackie K, Offertler L, Wang L, Kunos G

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Nutrition/Dietary Factors 1) Fish/DHA (Brain) DHA is deposited within the cerebral cortex at an accelerated rate during the last trimester of pregnancy and during the first 2 years after birth [10]
