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Dietary antioxidant vitamins and minerals and breast cancer risk: prospective results from the SUN cohort

There is evidence that the full inhibition of Complex I that prevents increased ROS generation impairs hypoxic adaptation in tumor cells by rewiring mitochondrial metabolism, and the antitumorigenic effect of ROS signaling is lost [39]

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Engineered nanomaterials: Risk perception, regulation and insurance

Furthermore, the protein disulfide isomerase (PDI) directly interacts with integrins, mediating disulfide-thiol exchange, resulting in conformational changes and activation (Popierlarski et al