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J., Greene, K
glutamicum was recorded as having ten times as much activity than E
In the liver, the 25-hydroxylase enzymes (CYP2R1 and CYP27A1) convert inactive cholecalciferol to 25(OH)VD 3 (calcidiol) by carbon 25 hydroxylation 14
These actions underscore the bidirectional modulation and multi-target integration that characterize acupunctures regulatory effects
This signaling promotes mitochondrial biogenesis and fatty acid oxidation, and indirectly facilitates a shift toward an anti-inflammatory M2 macrophage phenotype (34)
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