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[24] That observation is quietly profound for this articles theme: even in intact human physiology, local IGF-1 signaling can carry much of the growth load while circulating, protein-bound IGF-1 is dramatically reduced, which is exactly the local matters logic that made the MGF splice variant interesting in the first place

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demonstrated that mitochondria from mesenchymal stromal cells (MSCs) were taken up by endothelial cells through clathrin-independent endocytosis, but did not integrate

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Epidermal growth factor receptor mediated signal transduction pathway Epidermal growth factor receptor (EGFR) is a cell surface signaling protein that plays an essential role in stimulating cell proliferation and evading apoptosis

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Prodrugs are rationally designed inactive agents that are converted to cytotoxins preferentially and specifically in target tissues by enzymes that are specifically elevated in the tumor

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