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TF3 causes cell death in the OVCAR-3 cell line, which was derived from ovarian cancer (Gao et al., 2022)

Both pinoresinol and lariciresinol, precursors of enterolactone and enterodiol, are a structural moiety in lignin

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Smith PJ, Blumenthal JA, Babyak MA, Craighead L, Welsh-Bohmer KA, Browndyke JN, Strauman TA, Sherwood A

ApoE4 lowers age at onset in patients with frontotemporal dementia and tauopathy independent of amyloid-beta copathology

However, the increased expression of NF-B p65 in the mice of the vehicle control group was decreased significantly by L-carnitine or pioglitazone (a specific agonist of PPAR)