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Cpt1b ablation shifts immune cell function toward anti-inflammatory in skeletal muscle Another major characteristic of chronic inflammation in obesity is increased infiltration of pro-inflammatory immune cells in metabolic tissue when no source of infection or trauma is present 42

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In this study, the high molecular weight HA used in combination with AOD9604 may have further supported chondrocyte survival and matrix synthesis, contributing to the observed improvements in cartilage morphology and function

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