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Clinical differential diagnosis of this entity includes malignant melanoma, pigmented Basal Cell Carcinoma (BCC), and hemangioma.3 Histopathological differential diagnosis includes tumors with matrical differentiation, such as pilomatricoma with melanocytic hyperplasia, malignant pilomatricoma, matricoma, BCC with matrical differentiation3 and, most challengingly, malignant melanocytic matricoma, an extremely rare tumor with only 8 reported cases.5 Proposed criteria for differentiating benign and malignant melanocytic matricoma remain controversial2,5

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doi: 10.1210/en.2003-1740

Lcarnitine alleviates oxidative stressrelated damage via MAPK signaling in human lens epithelial cells exposed to H2O2