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Its unique structure, featuring a cyclohexane ring with oxygen-containing -ionone at both ends of the polyene chain enables AST to exhibit stronger antioxidant activity, being 1465 times more effective than vitamin C, vitamin E, and -carotene [4]

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10,278 Genetic suppression of the IKK/NF-B pathway, achieved through the deletion of one p65 allele, or pharmacological intervention via IKK inhibitors, such as 8K-NBD, has been shown to delay the onset and mitigate the severity of aging symptoms and age-related pathologies in the nervous system of murine models 10,279