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On the other hand, all samples under those groups that underwent vitamin B12 pre-treatment, regardless of dosage, one day prior to PTZ injection experienced simple less aggressive twitches, which are twitches of less duration and violent contractions, while the majority of samples under those groups that underwent vitamin B12 pre-treatment, regardless of dosage, two weeks prior to PTZ injection showed more of simple less aggressive twitches rather than tonic-clonic convulsions

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