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Abnormal epigenetic landscapes drive cancer therapeutic resistance Alterations in the patterns of post-translational modifications (PTMs) have been extensively linked to cancer, whether considering the global level across the entire genome or the genetic information and functional status of cells

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The oxidase-like activity of Fe 3 O 4 and FeSAN as the comparative nanozymes were also evaluated at the same amount of Fe in pFeSAN (Supplementary Fig

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In patients with bone metastasis, IGFs produced by the bone matrix increase the collagenolytic and osteoblast activity of neoplastic cells, thus contributing to metastatic spread (Figure 1) [58,77,80]

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