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For patients with adequate levels, the injections are unlikely to deliver the dramatic results that marketing materials suggest

Additional educational content is available in the Research Library

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Therefore, rational and properly designed experiments that utilize this technology in CKD management are vital

Recent findings regarding miRNAs-mediated regulation of IGF-1 expression open new avenues for designing and developing nucleic acid-based therapeutic agents that can finely tune IGF-1 levels and confer protective effects in cardiovascular and metabolic disease-associated conditions