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10 Taking glycerophospholipid (GPL) for example, the level of structural-defined molecule requires annotations of the lipid head group, the alkyl chain length, the desaturation degree, the position of carbon-carbon double bonds (C=C), the substitutional positions of alkyl chains to the glycerol backbone ( i.e

Nat Rev Mol Cell Biol 27 , 433449 (2026)

Apo C1 is the smallest exchangeable protein in this group and is synthesised in the liver, where like apo C3, the most abundant of the group, it inhibits lipoprotein lipase

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Thus, the ratio of apoC-III (with its inhibitory role) and apoE (which mediates particle receptor-mediated clearance) on the remnant surface is potentially an important regulator of the metabolism of these lipoproteins [18]

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