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Stent, J D

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These aforementioned points, with or without therapy, would have a NO background

RP/MRD cells also showed upregulated ROS- and oxidative stressrelated pathways by multiomics (Figure 3, B and D, and Supplemental Figure 3, B, D, and G) and increased reducing activity, including glutathione metabolism (Figure 3C and Supplemental Figure 3C), consistent with an increase in ROS generation due to enhanced OXPHOS

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A significance level of less than 0.05 was considered statistically significant