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Abbreviations A: amyloid beta ACh: acetylcholine AD: Alzheimers disease BBB: bloodbrain barrier BDNF: brain-derived neurotrophic factor CIND: cognitive impairment, no dementia CNS: central nervous system ERGO: ergothioneine GABA: -amino butyric acid MCI: mild cognitive impairment mTOR: mammalian target of rapamycin NMDA: N-Methyl-D-aspartate NT5: neurotrophin 4/5 PD: Parkinsons disease References Halliwell B, Cheah IK, Tang RMY (2018) Ergothioneine - a diet-derived antioxidant with therapeutic potential

In future studies, exact mechanistic validation can be performed to confirm its direct targets in more complex in vivo models and systematically assess its safety for long-term use

(2003) reported that epithalon increased telomerase activity in human fetal fibroblasts and extended their replicative lifespan beyond the normal Hayflick limit

Known for its powerful anti-aging properties, it is one of the most sought-after ingredients in an array of products, from serums to creams

Aging cell 2020;19, e13188, doi: Isral, A

The World Anti-Doping Agency (WADA) added BPC-157 to its Prohibited List in 2022 under the S0 category (Non-Approved Substances)