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As shave and punch biopsies contain only the central portion of the lesion, the area of interface between the melanocytic lesion and normal skin is absent

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In additon, inhibitors against JNK suppressed the upregulated mRNA expression levels of G-CSF (Fig

Examination of the entire skin surface is also important, as sun damage (eg, actinic keratoses) and other pigmented lesions may provide clinical clues that a non-pigmented or hypopigmented lesion may be an amelanotic melanoma
