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Neurosci 13, 300

Eur Rev Med Pharmacol Sci (2017) 21(2 Suppl):519

Hochmuth, C.E., et al.,Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila

Indeed, synergy between levodopa and natural bioactives already has clinical precedent: istradefylline, modeled after caffeine's natural adenosine A 2 A antagonism, is used to reduce levodopa's off periods, while green tea's (+)catechin demonstrates COMT inhibition, potentially enhancing levodopa's duration of effect [4, 116, 118]
However, combining them requires careful clinical oversight particularly around glucose monitoring, since both GH restoration and GLP-1 signaling affect insulin dynamics

A prospective controlled study showed that supplementation with 200ug SeMet per day during pregnancy and postpartum, reduced the incidence of PPTD and hypothyroidism (58)
