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13, 54 Our mechanistic investigations demonstrated that BSO+L-PAM induced significant increases in mitochondrial depolarization, cleavage of caspase-3, caspase-9, poly ADP ribose polymerase and DNA fragmentation

Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites

Negative feedback role of astrocytes in shaping excitation in brain cell co-cultures

Macrophages rely on extracellular serine to suppress aberrant cytokine production

Weight loss appears necessary but is not always sufficient for fibrosis regression, which is why dedicated, longer trials with biopsy endpoints are needed

A recent study used a comprehensive approach to investigate the association between UA levels and neurodegenerative outcomes