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Vitamin B12 (B12) is an essential cofactor for two enzymes involved in onecarbon metabolism: methylmalonyl CoA mutase (reduced function of this enzyme results in increased serum methylmalonyl acid (MMA) levels) and methionine synthetase (this enzyme catalyzes the remethylmation of homocysteine to methionine)

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doi: 10.1124/mol.63.4.908

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 "Vitamin B12: Deficiency"
