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Molecular and Cellular Biology, 17 (9)

Front Neurosci 14:1003 Guerram M, Zhang L-Y, Jiang Z-Z (2016) G-protein coupled receptors as therapeutic targets for neurodegenerative and cerebrovascular diseases

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[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Farag A.A., Deal A.M., McKinney K.A., Thorp B.D., Senior B.A., Ebert C.S., Jr., Zanation A.M

This had never been done before because it has been very difficult and laborious to obtain the pure enzymes, but this study was now enabled by our recent method development to produce recombinant selenoproteins with internal Sec residues, such as the GPX isoenzymes

Interestingly, a study focused on lung carcinoma in radiation-exposed MAYAK workers compared to non-worker controls showed that methylation at one gene (coding for a tumor suppressor protein) occurred more often in carcinomas found in exposed workers than in non-worker controls, with a dose-dependent prevalence [107]