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With respect to the applicant's assertion that TERLIVAZ offers a treatment option for a patient population unresponsive to currently available treatments because among patients in the CONFIRM trial, patients that had failed prior therapy with available options achieved a statistically significant improvement in renal function with TERLIVAZ, we note that the applicant provided evidence from data on file for the clinical study report of the CONFIRM trial

This decline can have profound implications for our health, as glutathione is essential for neutralizing harmful free radicals and supporting our immune system

However, zinc therapy does not increase copper excretion in urine

Zhao P, Wei Y, Sun G, Xu L, Wang T, Tian Y, Chao H, Tu Y, Ji J

An X, Sarmiento C, Tan T, Zhu H

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