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The nanoparticles with stimuli-responsive function targeted for Alzheimer's treatment will be further discussed in the following section to achieve an in-depth understanding of their concept and pharmaceutical application for AD

We measured circulating levels of the following carnitine compounds: free carnitine [C0], acetylcarnitine [C2], propionylcarnitine [C3], malonylcarnitine [C3DC], butyrylcarnitine [C4], isovalerylcarnitine [C5], tiglylcarnitine [C5:1], hexanoylcarnitine [C6], octanoylcarnitine [C8], decanoylcarnitine [C10], decenoylcarnitine [C10:1], decadienoylcarnitine [C10:2], dodecanoylcarnitine [C12], myristoylcarnitine [C14], palmitoylcarnitine [C16], and octadecanoylcarnitine [C18]

After 24 hours at 37C under anaerobic conditions, a sample of culture supernatant was collected and quenched by addition of formic acid to a final concentration of 0.1%

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Similarly, the amide bonds between SA and amino groups in MSNs-ss-SA can be cleaved by amidase, leading to the release of SA [46]