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See WARNINGS, PRECAUTIONS and ADVERSE REACTIONS

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Research protocols for AOD-9604 typically involve relatively small daily doses

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Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy

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We received a new comment on the methodology requesting CMS to consider how to further integrate the acuity of patients into the behavioral assumption methodology and how to better account for acuity overall in the PDGM

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