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What this means for you is practical

Excessive intake of Vitamin B12, especially through supplements, can potentially cause skin problems like acne due to the vitamin's impact on the gene expression of skin bacteria

FDA drug approval is a full review process involving Phase IIII clinical trials, demonstrated safety and efficacy in humans, and post-market surveillance obligations

Why these results differ is not entirely clear, but it may involve the use of distinct cell lines, different methods and/or exposure conditions

NKG2D can recognize MICA/B (soluble MHC Class I molecule-related protein), which is the only receptor that can be recognized with MICA/B found in vivo so far