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Whether these phenotypes are linked to the general function of the Phe-loop is unclear

Reconstituted peptides are thermally unstable and begin degrading within hours at room temperature

[35] Modeling [edit] Theoreticians have for decades hypothesized about the potential electrical function of spines, yet our inability to examine their electrical properties has until recently stopped theoretical work from progressing too far

O., Ashiagbor, G

A., Aisen, A

Among the numerous partners that interact with NRF2 regulating its activity, two members of the CNC-bZIP protein family BTB and CNC homolog 1 (BACH1) and BTB and CNC homolog 2 (BACH2) are two negative regulators of NRF2: they compete with NRF2 for the binding to ARE sequences of target genes, thereby preventing the production of antioxidant enzymes and cellular defense against toxicity [232, 233]