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While glutathione itself crosses this barrier poorly, the brain can synthesize glutathione from precursor amino acids, and systemic glutathione elevation may indirectly support brain glutathione status through various mechanisms including reduced oxidative stress on blood-brain barrier integrity and improved availability of glutathione precursors

[85] observed that nanocomposites made of combinations of activated carbon, bentonite, and aluminium oxide eliminated up to 87 % of mycotoxins
doi:10.1152/ajpcell.00252.2015 148
When the transport of dopamine into synaptic vesicles is obstructed or VMAT2 is inhibited by drugs such as tetrabenazine and reserpine, excessive dopamine can accumulate in the cytoplasm, leading to the auto-oxidation of dopamine and the formation of harmful by-products, eventually leading to neurodegeneration
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[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Stark SE & Caton AJ Antibodies that are specific for a single amino acid interchange in a protein epitope use structurally distinct variable regions
