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Therefore, estrogen dominance and progesterone resistance in endometriosis decrease autophagy levels through the activation of the CXCL12/CXCR4 axis (17,18)

thus, the ratio of SAM/SAH would be altered consistently with NTDs [84]

In mice, the high level of HCy (hyperhomocysteinemia) determines cognitive impairment linked to synaptic remodeling of cortex neurons and induces a decreased expression of the transcription factors HES1 and HES5, which play a role in neuronal regeneration [107]

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C., McAlister, F

Chronic SIBO causes demonstrable ENS neurodegeneration via bacterial toxin exposure and chronic inflammation
