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Newer evidence suggests that presence of mucus plugs increases all-cause mortality in COPD patients even in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage 1 and proposes an early role for thiol based mucolytics for better disease outcomes (18, 19)

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317 Combination therapy should also be personalized according to patient characteristics as monotherapy does

10.1016/j.cell.2015.10.001 [DOI] [PMC free article] [PubMed] [Google Scholar] Sies H

Omega-3 fatty acids is an essential fatty acid for the human body, which is easily obtained through food and other means, and has efficacy for a variety of diseases in terms of NDDs, and previous studies have shown that Omega-3 polyunsaturated fatty acids (PUFAs), particularly EPA and DHA, have been studied for their potential effectiveness in alleviating symptoms of ADHD

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