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the thermal unfolding of both forms interestingly showed a three-state model including a stable intermediate species, and they exhibited remarkable temperature stability owing to strong electrostatic interactions but were sensitive toward GdnHCl (Pica et al., 2012)

Hypoxia induces production of pro-angiogenic factors leading to enhanced, rapid and chaotic blood vessel formation

Results We used the GSH/GSSG-Glo Assay to monitor GSH and GSSG levels and observe the oxidative stress in adherent HEK-293 cells and suspension K-562 cells dosed with menadione (Figures 3 and 4)

It is the most abundant intracellular antioxidant in mammalian cells, existing in reduced (GSH) and oxidised (GSSG) forms the ratio between them serving as a widely used indicator of cellular oxidative stress in research

In addition, low levels of CAT activity were observed in NASH patients, suggesting a reduced scavenging capacity of the antioxidant system