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The rat MCL study showed progressive improvement at 14, 30, 45, and 90 days
Suspensions were disrupted by Fast-Prep (6.5 m/s, 45 s) twice and samples were cooled on ice between the cycles
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To show that the sphincters failure is a part of the NSAIDs-toxicity, COX-1 and COX-2 inhibitors were used in dose regimens shown to induce gastric and small intestine ulcers, hepatotoxicity and encephalopathy (8-14)
MTT, resazurin, ATP-luminescence, and LDH assays measure different aspects of cell condition
