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With cuprizone exposure, the recruitment of T-cells to the lesion site [70] may result from the decreased BBB integrity induced by cuprizone [75, 76] Cuprizone toxicity produces profound demyelination in the white and grey matter of the brain that mirrors sites of MS pathology [46]

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Smaller applicators come in 3 different varieties: CoolCore is the applicator is used in case there is excessive abdominal fat and that is why the applicator features a curved shape

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This means they lack the quality controls, dosing standardization, and safety monitoring that approved drugs provide

"We will utilize GPS-enabled thermal sensors in every thermal shipper with a control tower that will track the location and temperature of each vaccine shipment across their pre-set routes," she said