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Although our analyses demonstrate notable associations between GLO-1 expression and several cancer-related features, it is important to recognize that these findings remain correlative and do not establish causality
Golpon HA, Coldren CD, Zamora MR, Cosgrove GP, Moore MD, Tuder RM, Geraci MW, Voelkel NF: Emphysema lung tissue gene expression profiling

The addition of BCH to breast cancer cells can effectively suppress their proliferation and colony formation (Liang et al., 2011)
Once acetoacetate reaches extrahepatic tissues, it is converted back to acetyl-CoA that can enter the citric acid cycle to produce ATP

McKeever et al., 2025)
To evaluate whether LOsG induces ROS homeostasis disorder, a timely intraperitoneal injection of GSH (50 mg/kg/6 h) was made into animals challenged with LOsG as described above (LOsG.TdGSH group, n = 10)