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How tirzepatide works through dual GIP and GLP-1 receptor activation Tirzepatide activates two distinct incretin receptors simultaneously

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It helps in breaking down fats and proteins

This pulls the fatty tissue away from the muscle underneath

Search strategy We comprehensively searched PubMed, Embase, Cochrane Library, Web of Science, and clinical trials registries ( up until April 29, 2024, for randomized controlled trials (RCTs) that compared the efficacy of once-weekly tirzepatide with placebo in adults with T2D or without T2D