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Diabetic neuropathy often affects the feet and legs first, although it can also affect the hands

Strhle A, Richter M, Gonzlez-Gross M, et al

An excess of belly fat can also lead to hypertension, insulin resistance, and cardiovascular disease

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Patients using them seem to have an edge but they also fit into the category of patients who were already likely to be more successful in their rehab secondary to other internal/external factors
