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Acute administration effects suggest alternative metabolic mechanisms involving direct effects on cellular oxidative capacity

Overview 5-Amino-1MQ is classified as a potent and selective NNMT inhibitor that appears to preserve both S-adenosylmethionine (SAM) and nicotinamide, potentially enhancing NAD+ availability and cellular energetics

A blood test is initially carried out to determine a deficiency before a treatment plan is devised and implemented

In most cases, side effects are brief and disappear within a couple of days

Patients with severe, longstanding deficiency typically require longer recovery periods, with haematological improvement occurring over weeks and neurological recovery potentially taking months