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However, these approaches have significant limitations, as animal models do not recapitulate the polygenic nature of the disease, and post-mortem studies may be hampered by delays in tissue preservation which interfere with RNA, DNA and protein preservation, making molecular and biochemical studies biased

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The study developed a grading system for AMD lesions, focusing on advanced AMD outcomes such as neovascular AMD and central geographic atrophy

The high-carnitine diet down-regulated the mRNA levels of several lipolytic genes ( CPT1A , ATGL and HSL ), in agreement with the increased lipid content in muscle

In addition, incorporating biomarkers of oxidative stress into the screening process would be valuable

Neurocognitive and functional outcomes in persons recovering from West Nile virus illness